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	<title>dystrophin-glycoprotein complex &#8211; BIOENGINEER.ORG</title>
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	<title>dystrophin-glycoprotein complex &#8211; BIOENGINEER.ORG</title>
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		<title>Scaffold Protein SH3BP2 Revealed as Key to Muscle Strength at the Neuromuscular Junction</title>
		<link>https://bioengineer.org/scaffold-protein-sh3bp2-revealed-as-key-to-muscle-strength-at-the-neuromuscular-junction/</link>
		
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		<pubDate>Sat, 17 Oct 2026 11:08:42 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[acetylcholine receptors]]></category>
		<category><![CDATA[alpha-dystrobrevin-1]]></category>
		<category><![CDATA[dystrophin-glycoprotein complex]]></category>
		<category><![CDATA[Knockout mice]]></category>
		<category><![CDATA[molecular neuroscience]]></category>
		<category><![CDATA[muscle strength]]></category>
		<category><![CDATA[neuromuscular junction]]></category>
		<category><![CDATA[rapsyn]]></category>
		<category><![CDATA[scaffold protein]]></category>
		<category><![CDATA[SH3BP2]]></category>
		<category><![CDATA[skeletal muscle]]></category>
		<category><![CDATA[synaptic transmission]]></category>
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					<description><![CDATA[Researchers have discovered that the scaffold protein SH3BP2, previously known for its role in immune and bone cells, is essential for clustering acetylcholine receptors at the neuromuscular junction, and mice lacking it in muscle develop fragmented synapses, impaired transmission, and reduced strength.]]></description>
		
		
		
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