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	<title>dual-target therapeutics &#8211; BIOENGINEER.ORG</title>
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		<title>Computational Study Flags Benzimidazole Compounds That May Fight Inflammation and Allergy at Once</title>
		<link>https://bioengineer.org/computational-study-flags-benzimidazole-compounds-that-may-fight-inflammation-and-allergy-at-once/</link>
		
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		<pubDate>Tue, 06 Oct 2026 20:25:40 +0000</pubDate>
				<category><![CDATA[Chemistry]]></category>
		<category><![CDATA[ADMET prediction]]></category>
		<category><![CDATA[benzimidazole]]></category>
		<category><![CDATA[computer-aided drug design]]></category>
		<category><![CDATA[COX-2 inhibition]]></category>
		<category><![CDATA[drug-likeness]]></category>
		<category><![CDATA[dual-target therapeutics]]></category>
		<category><![CDATA[Glide XP docking]]></category>
		<category><![CDATA[histamine H1 receptor]]></category>
		<category><![CDATA[molecular docking]]></category>
		<category><![CDATA[ProTox-III]]></category>
		<category><![CDATA[structure-activity relationship]]></category>
		<category><![CDATA[SwissADME]]></category>
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					<description><![CDATA[A computational study of eleven novel benzimidazole derivatives identified three compounds, SP2, SP8, and SP11, that outperform ibuprofen and astemizole in predicted binding to both COX-2 and the histamine H1 receptor, positioning them as candidates for dual anti-inflammatory and antihistamine drug development.]]></description>
		
		
		
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