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		<title>Orphan Nuclear Receptor Ligands Trigger Ferroptosis and Reshape Immunity in Colon Cancer</title>
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		<pubDate>Thu, 08 Oct 2026 23:21:34 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[CD8+ T cells]]></category>
		<category><![CDATA[colon cancer]]></category>
		<category><![CDATA[DIM-3,5 ligands]]></category>
		<category><![CDATA[ferroptosis]]></category>
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		<category><![CDATA[immunotherapy]]></category>
		<category><![CDATA[Myeloid-derived suppressor cells]]></category>
		<category><![CDATA[NR4A1]]></category>
		<category><![CDATA[NR4A2]]></category>
		<category><![CDATA[nuclear receptors]]></category>
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					<description><![CDATA[New research shows that synthetic ligands for the orphan nuclear receptors NR4A1 and NR4A2 induce iron-dependent cell death in colon cancer cells while reprogramming the tumor immune microenvironment to enhance immune surveillance.]]></description>
		
		
		
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