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	<title>Cross-kingdom immune conservation &#8211; BIOENGINEER.ORG</title>
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		<title>Phosphorylation Blocks TIR Immune Signalling to Sustain Growth</title>
		<link>https://bioengineer.org/phosphorylation-blocks-tir-immune-signalling-to-sustain-growth/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Mon, 09 Jun 2025 14:24:31 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[Cross-kingdom immune conservation]]></category>
		<category><![CDATA[Growth-defense balance]]></category>
		<category><![CDATA[Immune signaling regulation]]></category>
		<category><![CDATA[NADase enzymatic inhibition]]></category>
		<category><![CDATA[TIR domain phosphorylation]]></category>
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					<description><![CDATA[Toll/interleukin-1 receptor (TIR) domain-containing proteins have long been recognized as critical components of immune signaling pathways across diverse organisms, orchestrating defense mechanisms that protect cells from pathogenic threats. These proteins, pivotal in both plant and animal systems, function enzymatically by cleaving nicotinamide adenine dinucleotide (NAD⁺), a ubiquitous coenzyme involved in redox reactions and cellular metabolism. [&#8230;]]]></description>
		
		
		
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