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		<title>Melanoma&#8217;s Deadly Shift: DNA Methylation Rewrites the Tumor as It Spreads</title>
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				<category><![CDATA[Health]]></category>
		<category><![CDATA[BRAF]]></category>
		<category><![CDATA[CIMP]]></category>
		<category><![CDATA[DNA Methylation]]></category>
		<category><![CDATA[epigenetics]]></category>
		<category><![CDATA[melanoma]]></category>
		<category><![CDATA[Metastasis]]></category>
		<category><![CDATA[NRAS]]></category>
		<category><![CDATA[paired tumor samples]]></category>
		<category><![CDATA[prognosis]]></category>
		<category><![CDATA[RRBS]]></category>
		<category><![CDATA[tumor microenvironment]]></category>
		<category><![CDATA[tumor mutation burden]]></category>
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					<description><![CDATA[A paired-sample study of 38 melanoma patients reveals that metastases undergo coordinated DNA methylation reprogramming largely independent of driver mutations, with tumor mutation burden dropping in a subset of spreading tumors.]]></description>
		
		
		
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