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		<title>Rare Prenatal Duplication on Chromosome 16 Reveals a Genetic Puzzle With Mostly Reassuring Outcomes</title>
		<link>https://bioengineer.org/rare-prenatal-duplication-on-chromosome-16-reveals-a-genetic-puzzle-with-mostly-reassuring-outcomes/</link>
		
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		<pubDate>Mon, 19 Oct 2026 20:36:48 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[16p13.11 microduplication]]></category>
		<category><![CDATA[amniocentesis]]></category>
		<category><![CDATA[chromosomal microarray analysis]]></category>
		<category><![CDATA[copy-number variant]]></category>
		<category><![CDATA[developmental delay]]></category>
		<category><![CDATA[genetic counseling]]></category>
		<category><![CDATA[genotype-phenotype correlation]]></category>
		<category><![CDATA[incomplete penetrance]]></category>
		<category><![CDATA[low-copy repeats]]></category>
		<category><![CDATA[NDE1]]></category>
		<category><![CDATA[prenatal diagnosis]]></category>
		<category><![CDATA[ventricular septal defect]]></category>
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					<description><![CDATA[A decade-long Chinese cohort study followed 19 fetuses with 16p13.11 microduplication and found that most children developed normally, highlighting the variant's incomplete penetrance and the challenges it poses for prenatal counseling.]]></description>
		
		
		
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