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	<title>cell death signalling &#8211; BIOENGINEER.ORG</title>
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		<title>Scientists Identify HERC4 as the Molecular Switch That Turns TNF Survival Signals Into Cell Death</title>
		<link>https://bioengineer.org/scientists-identify-herc4-as-the-molecular-switch-that-turns-tnf-survival-signals-into-cell-death/</link>
		
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		<pubDate>Mon, 12 Oct 2026 09:37:54 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[Apoptosis]]></category>
		<category><![CDATA[cell death signalling]]></category>
		<category><![CDATA[Drug development]]></category>
		<category><![CDATA[HERC4]]></category>
		<category><![CDATA[inflammation]]></category>
		<category><![CDATA[inflammatory bowel disease]]></category>
		<category><![CDATA[necroptosis]]></category>
		<category><![CDATA[psoriasis]]></category>
		<category><![CDATA[Rheumatoid arthritis]]></category>
		<category><![CDATA[RIPK1]]></category>
		<category><![CDATA[TNF]]></category>
		<category><![CDATA[Ubiquitination]]></category>
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					<description><![CDATA[Researchers have discovered that the protein HERC4 acts as the critical molecular switch that converts TNF survival signalling into cell death, opening a route to new oral therapies for chronic inflammatory diseases.]]></description>
		
		
		
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