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		<title>Climbing the causal ladder: a new framework sorts real cancer drug targets from statistical noise</title>
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					<description><![CDATA[A new evidence-accounting framework called the Causal Integration Ladder separates statistical association from causal, therapeutically tractable mechanism in cervical cancer, applying five evidence levels to TCGA-CESC genomic data and showing that even promising candidates like CDKN2A and CDC20 lack complete causal validation.]]></description>
		
		
		
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		<title>Time as an indispensable causal dimension in cardiovascular diseases: toward a four-dimensional biology</title>
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		<pubDate>Sat, 17 Oct 2026 15:08:42 +0000</pubDate>
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					<description><![CDATA[Heart failure does not begin when a cardiologist makes the diagnosis. By the time an ejection fraction falls below 40 percent, or an atrium lapses into persistent fibrillation, the underlying biology has usually been unfolding for years, sometimes decades. That]]></description>
		
		
		
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		<title>Genetic Evidence Points to Brain&#8217;s Triple Network as a Driver of Stroke Recovery</title>
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		<pubDate>Sat, 17 Oct 2026 15:01:00 +0000</pubDate>
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					<description><![CDATA[A Mendelian randomization study of 191 brain imaging phenotypes and 1,270 stroke patients finds genetic evidence that triple-network connectivity causally supports motor and cognitive recovery, and that LDL cholesterol may impair cognitive outcomes partly through this network.]]></description>
		
		
		
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