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	<title>cardiotoxicity &#8211; BIOENGINEER.ORG</title>
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		<title>Immune Cells That Attack the Heart: Multi-Omics Study Reveals Signature of Checkpoint Inhibitor Myocarditis</title>
		<link>https://bioengineer.org/immune-cells-that-attack-the-heart-multi-omics-study-reveals-signature-of-checkpoint-inhibitor-myocarditis/</link>
		
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		<pubDate>Wed, 14 Oct 2026 00:49:51 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[biomarkers]]></category>
		<category><![CDATA[Cancer immunotherapy]]></category>
		<category><![CDATA[cardiotoxicity]]></category>
		<category><![CDATA[CCL2/CCR2 axis]]></category>
		<category><![CDATA[CD8+ T cells]]></category>
		<category><![CDATA[Immune checkpoint inhibitors]]></category>
		<category><![CDATA[ISG15]]></category>
		<category><![CDATA[JAK/STAT pathway]]></category>
		<category><![CDATA[monocytes]]></category>
		<category><![CDATA[Myocarditis]]></category>
		<category><![CDATA[Proteomics]]></category>
		<category><![CDATA[single-cell RNA sequencing]]></category>
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					<description><![CDATA[A multi-omics study identifies ISG15-positive CD8 T cells and a CCL2-CCR2-mediated inflammatory loop as drivers of immune checkpoint inhibitor-induced myocarditis, yielding an eight-protein diagnostic panel and JAK-STAT inhibition as a dual-benefit therapy.]]></description>
		
		
		
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