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	<title>c-di-GMP signalling &#8211; BIOENGINEER.ORG</title>
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		<title>Biofilm Tolerance Emerges as Key Driver of Antibiotic Treatment Failure</title>
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		<pubDate>Sat, 24 Oct 2026 15:52:33 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[anti-biofilm therapy]]></category>
		<category><![CDATA[Antimicrobial Resistance]]></category>
		<category><![CDATA[antimicrobial tolerance]]></category>
		<category><![CDATA[bacteriophage therapy]]></category>
		<category><![CDATA[biofilms]]></category>
		<category><![CDATA[c-di-GMP signalling]]></category>
		<category><![CDATA[efflux pumps]]></category>
		<category><![CDATA[extracellular polymeric substance]]></category>
		<category><![CDATA[Horizontal gene transfer]]></category>
		<category><![CDATA[Persister cells]]></category>
		<category><![CDATA[quorum sensing]]></category>
		<category><![CDATA[stringent response]]></category>
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					<description><![CDATA[A new review argues that antibiotic failure in biofilm infections often begins with reversible physiological tolerance rather than genetic resistance, and maps the molecular pathways that could be targeted before stable resistance evolves.]]></description>
		
		
		
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