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	<title>BMP2 GREM1 axis &#8211; BIOENGINEER.ORG</title>
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		<title>SPP1 Crucial for Pancreatic Cancer Cell Fate</title>
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		<pubDate>Wed, 24 Sep 2025 16:42:04 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[BMP2 GREM1 axis]]></category>
		<category><![CDATA[mesenchymal cell fate]]></category>
		<category><![CDATA[paracrine signaling]]></category>
		<category><![CDATA[SPP1 pancreatic cancer]]></category>
		<category><![CDATA[tumor heterogeneity]]></category>
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					<description><![CDATA[In a groundbreaking study published in Nature, researchers have unraveled a crucial cellular dialogue that sustains pancreatic ductal adenocarcinoma (PDAC), one of the deadliest forms of cancer due to its notorious resistance to therapy and aggressive progression. The investigation reveals an intricate paracrine network between epithelial and mesenchymal cancer cell populations, mediated by three diffusible [&#8230;]]]></description>
		
		
		
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