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	<title>bedaquiline &#8211; BIOENGINEER.ORG</title>
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		<title>Bedaquiline&#8217;s solubility problem: advanced formulation strategies for optimized tuberculosis therapy</title>
		<link>https://bioengineer.org/bedaquilines-solubility-problem-advanced-formulation-strategies-for-optimized-tuberculosis-therapy/</link>
		
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		<pubDate>Sat, 17 Oct 2026 19:12:02 +0000</pubDate>
				<category><![CDATA[Chemistry]]></category>
		<category><![CDATA[bedaquiline]]></category>
		<category><![CDATA[Drug delivery]]></category>
		<category><![CDATA[drug solubility]]></category>
		<category><![CDATA[Enhancing]]></category>
		<category><![CDATA[MDR-TB]]></category>
		<category><![CDATA[nanoemulsion]]></category>
		<category><![CDATA[Pharmaceutical Formulation]]></category>
		<category><![CDATA[polymeric micelles]]></category>
		<category><![CDATA[solid dispersion]]></category>
		<category><![CDATA[solid lipid nanoparticles]]></category>
		<category><![CDATA[solubility]]></category>
		<category><![CDATA[Tuberculosis]]></category>
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					<description><![CDATA[A comprehensive review in Discover Chemistry evaluates advanced formulation strategies, from solid dispersions and novel salt forms to polymeric micelles and inhalable nanoparticles, designed to overcome bedaquiline's extraordinarily poor aqueous solubility and unlock its full therapeutic potential against multidrug-resistant tuberculosis.]]></description>
		
		
		
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