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	<title>autoinflammatory diseases &#8211; BIOENGINEER.ORG</title>
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		<title>New Dashboard Brings Protein Structure Into the Hunt for Disease-Causing Gene Variants</title>
		<link>https://bioengineer.org/new-dashboard-brings-protein-structure-into-the-hunt-for-disease-causing-gene-variants/</link>
		
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		<pubDate>Tue, 13 Oct 2026 15:08:36 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[ACMG/AMP]]></category>
		<category><![CDATA[autoinflammatory diseases]]></category>
		<category><![CDATA[Bioinformatics]]></category>
		<category><![CDATA[ClinVar]]></category>
		<category><![CDATA[genetic diagnosis]]></category>
		<category><![CDATA[inborn errors of immunity]]></category>
		<category><![CDATA[missense variants]]></category>
		<category><![CDATA[Protein Structure`]]></category>
		<category><![CDATA[structural biology]]></category>
		<category><![CDATA[variant interpretation]]></category>
		<category><![CDATA[variant prioritization]]></category>
		<category><![CDATA[Variants of uncertain significance]]></category>
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					<description><![CDATA[Researchers have developed ProtSAVI, an R-based dashboard that combines protein structure analysis with ACMG/AMP criteria to reclassify variants of uncertain significance in immune disease genes.]]></description>
		
		
		
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