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		<title>Lung Cancer Rewrites Its Identity: Rare Squamous Transformation Tracked by Genomic Sequencing</title>
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				<category><![CDATA[Health]]></category>
		<category><![CDATA[ATM]]></category>
		<category><![CDATA[case report]]></category>
		<category><![CDATA[EGFR-TKI resistance]]></category>
		<category><![CDATA[histologic transformation]]></category>
		<category><![CDATA[immunotherapy]]></category>
		<category><![CDATA[lineage plasticity]]></category>
		<category><![CDATA[lung adenocarcinoma]]></category>
		<category><![CDATA[next-generation sequencing]]></category>
		<category><![CDATA[Osimertinib]]></category>
		<category><![CDATA[Smad4]]></category>
		<category><![CDATA[squamous cell carcinoma]]></category>
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					<description><![CDATA[A case report documents an EGFR-mutant lung adenocarcinoma transforming into squamous cell carcinoma after multiple therapies, with newly detected SMAD4 and ATM variants flagged as candidate but unproven contributors.]]></description>
		
		
		
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