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	<title>anti-invasive compounds &#8211; BIOENGINEER.ORG</title>
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		<title>Experimental Compounds Curb Glioblastoma Cell Invasion in Tissue Slice Models</title>
		<link>https://bioengineer.org/experimental-compounds-curb-glioblastoma-cell-invasion-in-tissue-slice-models/</link>
		
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		<pubDate>Tue, 27 Oct 2026 13:15:00 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[anti-invasive compounds]]></category>
		<category><![CDATA[AqB011]]></category>
		<category><![CDATA[aryl sulfonamide]]></category>
		<category><![CDATA[brain cancer]]></category>
		<category><![CDATA[Drug development]]></category>
		<category><![CDATA[Glioblastoma]]></category>
		<category><![CDATA[indole analogs]]></category>
		<category><![CDATA[RAD114]]></category>
		<category><![CDATA[RAD118]]></category>
		<category><![CDATA[temozolomide]]></category>
		<category><![CDATA[tumor invasion]]></category>
		<category><![CDATA[xenograft tissue slice co-culture]]></category>
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					<description><![CDATA[In ex vivo xenograft tissue slice co-cultures, indole analogs and the aryl sulfonamide AqB011 potently inhibited glioblastoma cell invasion into brain tissue, with RAD118 and AqB011 showing the strongest effects at a non-toxic concentration.]]></description>
		
		
		
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