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	<title>anti-glioma agents &#8211; BIOENGINEER.ORG</title>
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		<title>Oxadiazole compound shows potent selectivity against oligodendroglioma cells</title>
		<link>https://bioengineer.org/oxadiazole-compound-shows-potent-selectivity-against-oligodendroglioma-cells/</link>
		
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		<pubDate>Sat, 17 Oct 2026 17:54:29 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[1,3,4-oxadiazole]]></category>
		<category><![CDATA[anti-glioma agents]]></category>
		<category><![CDATA[derivatives]]></category>
		<category><![CDATA[drug-likeness]]></category>
		<category><![CDATA[HS683]]></category>
		<category><![CDATA[Kinase Inhibitors]]></category>
		<category><![CDATA[Medicinal Chemistry]]></category>
		<category><![CDATA[molecular docking]]></category>
		<category><![CDATA[MTT assay]]></category>
		<category><![CDATA[oligodendroglioma]]></category>
		<category><![CDATA[Oxadiazole]]></category>
		<category><![CDATA[selectivity index]]></category>
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					<description><![CDATA[Researchers have synthesized a series of 1,3,4-oxadiazole derivatives and evaluated their anticancer potential against HS683 human oligodendroglioma cells, identifying one compound, designated B2, as a lead candidate with an IC50 of 37.71 µg/mL and a selectivity index of 14.55. The]]></description>
		
		
		
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