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	<title>all-atom molecular dynamics &#8211; BIOENGINEER.ORG</title>
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		<title>High-Definition Simulations Reveal New Class of Protein Misfolding</title>
		<link>https://bioengineer.org/high-definition-simulations-reveal-new-class-of-protein-misfolding/</link>
		
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		<pubDate>Fri, 08 Aug 2025 20:26:34 +0000</pubDate>
				<category><![CDATA[Chemistry]]></category>
		<category><![CDATA[all-atom molecular dynamics]]></category>
		<category><![CDATA[computational protein biophysics]]></category>
		<category><![CDATA[neurodegenerative disease implications]]></category>
		<category><![CDATA[non-native entanglement]]></category>
		<category><![CDATA[protein misfolding mechanisms]]></category>
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					<description><![CDATA[In a groundbreaking study that advances our understanding of protein biophysics and misfolding phenomena, researchers at Penn State have utilized cutting-edge all-atom computer simulations to identify and characterize a novel class of protein misfolding known as non-native entanglement. This structural anomaly manifests when specific segments of a protein’s amino acid chain become inappropriately looped or [&#8230;]]]></description>
		
		
		
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