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	<title>aging women &#8211; BIOENGINEER.ORG</title>
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		<title>The X Chromosome That Vanishes: How Aging Women&#8217;s Blood Cells Lose a Sex Chromosome</title>
		<link>https://bioengineer.org/the-x-chromosome-that-vanishes-how-aging-womens-blood-cells-lose-a-sex-chromosome/</link>
		
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		<pubDate>Sun, 25 Oct 2026 02:39:05 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[aging women]]></category>
		<category><![CDATA[autoimmunity]]></category>
		<category><![CDATA[cell competition]]></category>
		<category><![CDATA[clonal hematopoiesis]]></category>
		<category><![CDATA[genome aging]]></category>
		<category><![CDATA[inactive X chromosome]]></category>
		<category><![CDATA[leukemia risk]]></category>
		<category><![CDATA[loss of X chromosome]]></category>
		<category><![CDATA[mosaic chromosomal alterations]]></category>
		<category><![CDATA[somatic mutation]]></category>
		<category><![CDATA[UK Biobank]]></category>
		<category><![CDATA[X-chromosome inactivation]]></category>
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					<description><![CDATA[A sweeping review of population-scale genomic data reveals that loss of the X chromosome is the most common mosaic chromosomal alteration in aging women, shaped by germline variants, environmental stressors, and the unique biology of the inactive X, with detectable associations spanning leukemia risk, autoimmunity, and cardiovascular disease.]]></description>
		
		
		
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