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	<title>Age-dependent sepsis survival &#8211; BIOENGINEER.ORG</title>
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	<title>Age-dependent sepsis survival &#8211; BIOENGINEER.ORG</title>
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		<title>Age-Related Tradeoffs in Mouse Disease Tolerance</title>
		<link>https://bioengineer.org/age-related-tradeoffs-in-mouse-disease-tolerance/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Thu, 15 Jan 2026 08:24:42 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Age-dependent sepsis survival]]></category>
		<category><![CDATA[Based on the content]]></category>
		<category><![CDATA[Cardiac disease tolerance]]></category>
		<category><![CDATA[Cardiac resilience**]]></category>
		<category><![CDATA[Disease tolerance]]></category>
		<category><![CDATA[FoxO1 transcription factor]]></category>
		<category><![CDATA[here are 5 appropriate tags: **Sepsis]]></category>
		<category><![CDATA[İçeriğe göre en uygun 5 etiket: **FoxO1-Trim63 axis]]></category>
		<category><![CDATA[MuRF1 in infection]]></category>
		<category><![CDATA[Sepsis therapeutic targets** * **FoxO1-Trim63 axis:** Çalışmanın merkezindeki moleküler mekanizmayı doğrudan vurgular. * **Cardiac disease tolerance:** Kalp özelinde hastalık toler]]></category>
		<category><![CDATA[Trim63 (MuRF1)]]></category>
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					<description><![CDATA[In a groundbreaking study published in Nature, researchers have unveiled a pivotal role for the transcription factor FoxO1 and its regulation of the atrogene Trim63 in protecting young mice from the deleterious effects of polymicrobial sepsis. This discovery sheds light on age-dependent mechanisms of cardiac resilience during severe systemic infections, revealing critical insights with potential [&#8230;]]]></description>
		
		
		
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