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	<title>acetate supplementation &#8211; BIOENGINEER.ORG</title>
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	<title>acetate supplementation &#8211; BIOENGINEER.ORG</title>
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		<title>ZEB1-TEAD1 partnership keeps heart cells fueled and functioning</title>
		<link>https://bioengineer.org/zeb1-tead1-partnership-keeps-heart-cells-fueled-and-functioning/</link>
		
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		<pubDate>Fri, 23 Oct 2026 21:29:10 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[ACAA2]]></category>
		<category><![CDATA[acetate supplementation]]></category>
		<category><![CDATA[cardiac metabolism]]></category>
		<category><![CDATA[cardiomyocytes]]></category>
		<category><![CDATA[Fatty Acid Oxidation]]></category>
		<category><![CDATA[glycolysis]]></category>
		<category><![CDATA[heart failure]]></category>
		<category><![CDATA[Mitochondrial dysfunction]]></category>
		<category><![CDATA[Nature Communications]]></category>
		<category><![CDATA[PKM1]]></category>
		<category><![CDATA[TEAD1]]></category>
		<category><![CDATA[ZEB1]]></category>
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					<description><![CDATA[A mouse study in Nature Communications shows that the transcription factor ZEB1 works with TEAD1 to activate metabolic genes sustaining glycolysis and fatty acid oxidation in cardiomyocytes, and that its loss drives heart failure that acetate supplementation can partially rescue.]]></description>
		
		
		
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