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	<title>β2-microglobulin degradation &#8211; BIOENGINEER.ORG</title>
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	<title>β2-microglobulin degradation &#8211; BIOENGINEER.ORG</title>
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		<title>Tumor PD-L1 Triggers β2m Degradation to Evade Immunity</title>
		<link>https://bioengineer.org/tumor-pd-l1-triggers-%ce%b22m-degradation-to-evade-immunity/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Fri, 02 Jan 2026 06:18:31 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Cancer Immunotherapy Resistance]]></category>
		<category><![CDATA[geleneksel]]></category>
		<category><![CDATA[Intrinsic immune evasion** **Açıklama:** 1. **PD-L1 enzymatic activity:** Makalenin ana bulgusu]]></category>
		<category><![CDATA[İşte bu içerik için 5 uygun etiket: **PD-L1 enzymatic activity]]></category>
		<category><![CDATA[MHC-I antigen presentation]]></category>
		<category><![CDATA[PD-L1'in beklenmedik E3 ubiquitin ligaz aktivitesini keşfetmesidir. Bu]]></category>
		<category><![CDATA[β2-microglobulin degradation]]></category>
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					<description><![CDATA[In a groundbreaking development that challenges prevailing paradigms of cancer immunotherapy resistance, researchers have unveiled a novel intrinsic mechanism by which tumor cells circumvent the immune system’s cytotoxic T lymphocyte attack. The study, conducted by Zhao et al. and published in Cell Research in 2026, reveals that PD-L1, a protein traditionally recognized for its role [&#8230;]]]></description>
		
		
		
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