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	<title>β-catenin/TCF4/DDX17 feedback loop &#8211; BIOENGINEER.ORG</title>
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		<title>β-Catenin/TCF4 Pathway Drives DDX17-Mediated Epithelial-Mesenchymal Transition and Metastasis in Liver Cancer</title>
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		<pubDate>Thu, 18 Sep 2025 13:19:46 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[DDX17-mediated metastasis mechanisms]]></category>
		<category><![CDATA[Epithelial-mesenchymal transition in liver cancer]]></category>
		<category><![CDATA[Orthotopic HCC mouse models]]></category>
		<category><![CDATA[Therapeutic targeting of Wnt signaling]]></category>
		<category><![CDATA[β-catenin/TCF4/DDX17 feedback loop]]></category>
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					<description><![CDATA[A groundbreaking study from the Research Center for Preclinical Medicine at Southwest Medical University unveils new insights into the molecular drivers behind hepatocellular carcinoma (HCC) metastasis, highlighting the critical role of the DEAD-box RNA helicase DDX17. HCC, notorious for high morbidity and mortality rates worldwide, especially suffers from the aggressive nature of its metastatic spread, [&#8230;]]]></description>
		
		
		
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